Critical role of the gut
Along with the microbiome, it is also important to consider the physical structure of the gut, when thinking about digestive health. The gut mucosa is one of the most sophisticated interfaces in the body which acts as a dynamic barrier between the gut lumen and the internal systems. It plays a critical role in digestion and nutrient absorption, as well as immune defence and microbial regulation.
Maintaining a healthy gut mucosa
A healthy mucosa facilitates the selective absorption of nutrients while blocking the entry of harmful pathogens and toxins. The integrity of the mucosa is essential to maintaining immune homeostasis as when the barrier is compromised, with increased intestinal permeability, it can lead to systemic inflammation, dysbiosis, and a heightened risk of chronic disease, often known as “leaky gut syndrome”.
The microbiome maintains the mucosal barrier, by strengthening tight junctions between cells, promoting mucus production, and modulating inflammatory signalling pathways. In this way, a well-functioning microbiome directly supports the resilience and effectiveness of the mucosal barrier.
Disruption to the mucosa, be it through dysbiosis, infection, stress, antibiotics, poor diet, or chronic inflammation, can reduce its ability to absorb nutrients efficiently and defend the host. Clinically, this might manifest as diarrhoea, malnutrition, recurring infections, or systemic signs of inflammation. Supporting mucosal health, therefore, is not just about treating disease but maintaining optimal function in animals across all life stages.
In practice, maintaining mucosal integrity means considering a range of supportive strategies, from dietary fibre and balanced nutrition to microbial support and targeted supplementation. Products such as ProRestore+, a triple-action symbiotic, assist this approach. ProRestore+ combines prebiotics to fuel beneficial bacteria, probiotics to replenish microbial populations, postbiotics to deliver beneficial bacterial metabolites that enhance gut barrier function and immune signalling and includes plasma protein, which supports mucosal integrity and immune response, especially during acute gastrointestinal upset or recovery from illness.
Using faecal testing as a diagnostic tool
Digestive health plays a vital role in the overall wellbeing of animals, and identifying gut-related issues early can make a significant difference in treatment outcomes. Faecal testing is a key diagnostic tool that helps uncover underlying causes of gastrointestinal symptoms, from parasitic infections to imbalances in gut flora. Through our sister company, NationWide Laboratories, NVS offers access to a comprehensive range of faecal tests designed to support accurate diagnosis and effective treatment planning. Explore the options available and learn why faecal testing is an essential step in managing digestive health.
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